CALSPORIN®

Optimizing the gut microbiota for livestock

Poultry Swine Cattle Horse Quail

CALSPORIN®: Proven safety for more than 35 years of usage.

  • CALSPORIN® is a live microbial product for poultry, swine, cattle, horse and etc. containing Bacillus subtilis as its active ingredient.
  • In Japan, it was approved as feed additives (Classification = Probiotics) effective for improving productivity, including improving growth and feed conversion rates, for swine and cattle in 1995 and for poultry in 1996.
  • U.S. : Listed in the official publication issued by AAFCO as a type of microorganism reviewed by the FDA as “Generally Recognized As Safe (GRAS)” for use as feed from a safety perspective. Available as “Direct-Fed Microorganisms (DFMs)” found to present no safety concern.
  • Europe : Authorized as a zootechnical feed additive (functional group: gut flora stabilizer) by the European Food Safety Authority and meets all safety standards in the EU guidelines.
  • CALSPORIN® ORGANIC is listed by OMRI (the US Organic Materials Review Institute) for organic production.

Application & Features

  • Bacillus subtilis, the active ingredient in CALSPORIN®, is an aerobic bacterium. It is not an intestinal bacterium, therefore, it does not colonize in the intestines nor does it propagate like indigenous intestinal bacteria. When CALSPORIN® is supplied at a single dose, they pass through the alimentary track with feces in few hours to several days. Daily supplementation of CALSPORIN® is strongly recommended for livestock species that are constantly exposed to many and different types of stress.


  • CALSPORIN® is a highly stable product that is heat-resistant and accommodates well with pelletizing process since Bacillus subtilis can form endospore (spore form).

Product form

Bacillus subtilis C-3102


About CALSPORIN®


About CALSPORIN® in Spanish

About CALSPORIN® in Portuguese

About CALSPORIN® in Chinese

Expressions or figures shown in above videos have been checked to comply with Japanese regulations.